Andiroba Oil from Raintree Nutrition - Andiroba - Carapa guianensis - Andiroba - Carapa guianensis - Andiroba - Carapa guianensis - Andiroba - Carapa guianensis Andiroba Oil

Carapa guianensis


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Andiroba Oil is an emollient nut oil which has been processed from the seeds or nuts of the Amazonian tree, Carapa guianensis. The Indians in the Amazon have used andiroba oil for centuries as a natural insect repellent.* Chemical analysis of andiroba oil has identified the presence of a group of chemicals called limonoids. The anti-inflammatory and insect repellent properties of andiroba oil are attributed to the presence of these limonoids, including a novel one which has been named andirobin.* For more information on andiroba go to the Tropical Plant Database. To see pictures of andiroba click here.

Traditional Uses:* for insect bites and stings; as an insect repellant; for psoriasis, dermatitis, heat rash, skin fungi, and other skin problems; for skin parasites; for skin cancer

Suggested Use: Apply directly to skin as desired.
Contraindications: Not to be used internally during pregnancy or while breast-feeding.
Drug Interactions: None reported.





Third-Party Published Research*

All available third-party research on andiroba can be found at PubMed. A partial listing of the published research on andiroba is shown below:


Insect Repellant & Insecticidal Actions:
Vendramini, M., et al. "Action of andiroba oil (Carapa guianensis) on Rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae) semi-engorged females: Morphophysiological evaluation of reproductive system." Microsc Res Tech. 2012 Dec;75(12):1745-54.
Vendramini, M., et al. "Cytotoxic effects of andiroba oil (Carapa guianensis) in reproductive system of Rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae) semi-engorged females." Parasitol Res. 2012 Nov;111(5):1885-94.
Sarria, A., et al. "Effect of triterpenoids and limonoids isolated from Cabralea canjerana and Carapa guianensis (Meliaceae) against Spodoptera frugiperda (J. E. Smith)." Z Naturforsch C. 2011 May-Jun;66(5-6):245-50.
Prophiro, J., et al. "Evaluation of time toxicity, residual effect, and growth-inhibiting property of Carapa guianensis and Copaifera sp. in Aedes aegypti." Parasitol Res. 2012 Feb;110(2):713-9.
de Souza Chagas, A., et al. "In vitro efficacy of plant extracts and synthesized substances on Rhipicephalus (Boophilus) Microplus (Acari: Ixodidae)." Parasitol Res. 2012 Jan;110(1):295-303.
Roy, A., et al. “Limonoids: overview of significant bioactive triterpenes distributed in plants kingdom. Biol. Pharm. Bull. 2006; 29(2): 191-201.
de Mendonca, F. A., et al. “Activities of some Brazilian plants against larvae of the mosquito Aedes aegypti.” Fitoterapia. 2005 Dec; 76(7-8): 629-36.
Silva, O. S., et al. “The use of andiroba Carapa guianensis as larvicide against Aedes albopictus.” J. Am. Mosq. Control Assoc. 2004 Dec; 20(4): 456-7.
Miot, H. A., et al. “Comparative study of the topical effectiveness of the Andiroba oil (Carapa guianensis) and DEET 50% as repellent for Aedes sp.” Rev. Inst. Med. Trop. Sao Paulo. 2004 Sep-Oct; 46(5): 253-6.
Konan, Y. L., et al. “Comparison of the effect of two excipients (karite nut butter and vaseline) on the efficacy of Cocos nucifera, Elaeis guineensis and Carapa procera oil-based repellents formulations against mosquitoes biting in Ivory Coast.” Parasite. 2003 Jun; 10(2): 181-4.
Sylla, M., et al. “Evaluation of the efficacity of coconut (Cocos nucifera), palm nut (Eleais guineensis) and gobi (Carapa procera) lotions and creams in individual protection against Simulium damnosum S.L. bites in Cote d'Ivoire.” Bull. Soc. Pathol. Exot. 2003 May; 96(2): 104-9.
Gilbert, B., et al. "Activities of the Pharmaceutical Technology Institute of the Oswaldo Cruz Foundation with medicinal, insecticidal and insect repellent plants." An. Acad. Bras. Cienc. 1999; 71(2): 265-71.
Mikolajczak, K. L., et al. “A limonoid antifeedant from seed of Carapa procera.” J. Nat. Prod. 1988; 51(3): 606-10

Antiparasitic, Anti-malarial & Antiprotozoal Actions:
Miranda Júnior, R., et al. "Antiplasmodial activity of the andiroba (Carapa guianensis Aubl., Meliaceae) oil and its limonoid-rich fraction." J Ethnopharmacol. 2012 Aug 1;142(3):679-83.
Carvalho, C., et al. "The anthelmintic effect of plant extracts on Haemonchus contortus and Strongyloides venezuelensis." Vet Parasitol. 2012 Feb 10;183(3-4):260-8.
Mesquita, M. L., et al. “Antileishmanial and trypanocidal activity of Brazilian Cerrado plants.” Mem. Inst. Oswaldo Cruz. 2005 Nov; 100(7): 783-7.
MacKinnon, S., et al. “Antimalarial activity of tropical Meliaceae extracts and gedunin derivatives.” J. Nat. Prod. 1997; 60(4): 336-41.
Titanji, J. P., et al. “Novel Onchocerca volvulus filaricides from Carapa procera, Polyathia suaveolens and Pachypodanthium staudtii.” Acta. Leiden. 1990; 59: (1-2) 377-82.

Anti-Allergic Actions:
Penido, C., et al. “Inhibition of allergen-induced eosinophil recruitment by natural tetranortriterpenoids is mediated by the suppression of IL-5, CCL11/eotaxin and NFkappaB activation.” Int. Immunopharmacol. 2006; 6(2): 109-21.
Penido, C., et al. “Anti-allergic effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on allergen-induced vascular permeability and hyperalgesia.” Inflamm. Res. 2005; 54(7): 295-303.

Anti-Inflammatory & Pain-Relieving Actions:
Penido, C., et al. "Antiinflammatory effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on zymosan-induced arthritis in mice." Inflamm. Res. 2006; 55(11): 457-64.
Penido, C., et al. “Anti-allergic effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on allergen-induced vascular permeability and hyperalgesia.” Inflamm. Res. 2005; 54(7): 295-303.
Hammer, M. L., et al. “Tapping an Amazonian plethora: four medicinal plants of Marajó Island, Pará (Brazil).” J. Ethnopharmacol. 1993 Sep; 40(1): 53-75.

Wound Healing Actions:
Nayak, B., et al. "Investigation of the wound healing activity of Carapa guianensis L. (Meliaceae) bark extract in rats using excision, incision, and dead space wound models." J Med Food. 2010 Oct;13(5):1141-6.
Nayak, B., et al. "Experimental Evaluation of Ethanolic Extract of Carapa guianensis L. Leaf for Its Wound Healing Activity Using Three Wound Models." Evid. Based Complement. Alternat. Med. 2009 Oct 13.
Hammer, M. L., et al. “Tapping an Amazonian plethora: four medicinal plants of Marajó Island, Pará (Brazil).” J. Ethnopharmacol. 1993 Sep; 40(1): 53-75.

Cytotoxic and Anticancerous Actions:
Moura, M. D., et al. “Natural products reported as potential inhibitors of uterine cervical neoplasia.” Acta. Farm. Bonaerense. 2002; 21(1): 67-74.
Cohen, E., et al. “Cytotoxicity of nibolide, epoxyazadiradione and other liminoids from neem insecticide.” Life Sci. 1996; 58(13): 1075-81.
Hammer, M. L., et al. “Tapping an Amazonian plethora: four medicinal plants of Marajó Island, Pará (Brazil).” J. Ethnopharmacol. 1993 Sep; 40(1): 53-75.
Nakanishi, K., et al. “Phytochemical survey of Malaysian plants.” Chem. Pharm. Bull. 1965; 13(7): 882-890.

Immune Stimulant Actions:
Ferraris, F., et al. "Modulation of T lymphocyte and eosinophil functions in vitro by natural tetranortriterpenoids isolated from Carapa guianensis Aublet." Int Immunopharmacol. 2011 Jan;11(1):1-11.

Antimicrobial Actions (bacteria):
Nakanishi, K., et al. “Phytochemical survey of Malaysian plants.” Chem. Pharm. Bull. 1965; 13(7): 882-890.

Toxicity Studies (Non-toxic effects):
Costa-Silva, J., et al. "Acute and subacute toxicity of the Carapa guianensis Aublet (Meliaceae) seed oil." J. Ethnopharmacol. 2008 Mar 28; 116(3): 495-500.
Costa-Silva, J., et al. "A toxicological evaluation of the effect of Carapa guianensis Aublet on pregnancy in Wistar rats." J. Ethnopharmacol. 2007 May 30; 112(1): 122-6.

Chemical Constituents Identified:
da Silva, V., et al. Isolation of limonoids from seeds of Carapa guianensis Aublet (Meliaceae) by high-speed countercurrent chromatography." Phytochem. Anal. 2009 Jan; 20(1): 77-81.
Tappin, M., et al. "Development of an HPLC method for the determination of tetranortriterpenoids in Carapa guianensis seed oil by experimental design." J. Pharm. Biomed. Anal. 2008 Dec 1; 48(4): 1090-5.



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by the Food and Drug Administration. This product is
not intended to treat, cure, mitigate or prevent any disease.
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Last updated 2-11-2013