Agricultural Research Service - ARS

Dr. Duke's
Phytochemical and Ethnobotanical Databases

Chemicals and their Biological Activities in: Carapa guianensis AUBL. (Meliaceae) -- Andiroba


Chemicals

11-BETA-ACETOXYGEDUNIN Bark: HHB
Antimalarial IC50=3.11 ug/mL PR4:33 ; Pesticide DUKE1992B

6-ALPHA-ACETOXY-EPOXYAZADIRADIONE Plant: JSG
No activity reported.

6-ALPHA-ACETOXY-GEDUNIN Plant: JSG
No activity reported.

6-BETA-ACETOXY-GEDUNIN Seed: HHB
No activity reported.

6ALPHA,11BETA-DIACETOXY-GEDUNIN Bark: HHB
No activity reported.

6ALPHA-HYDROXYGEDUNIN Plant: JSG
No activity reported.

6BETA,11BETA-DIACETOXY-GEDUNIN Bark: HHB
No activity reported.

7-DEACETOXY-7-OXOGEDUNIN Plant: JSG
No activity reported.

7-DESACETOXY-7-KETOGEDUNIN Seed: HHB
No activity reported.

ANDIROBIN Seed: HHB
No activity reported.

EPOXYAZADIRADIONE Plant: JSG
No activity reported.

FAT Seed 550,000 - 650,000 ppm HHB
No activity reported.

OLEIC-ACID Seed 275,000 - 375,000 ppm HHB
5-Alpha-Reductase-Inhibitor PMID10830511 ; Allergenic M&R495 ; Anemiagenic DUKE1992B ; Antiinflammatory IC50=21 uM POP:153 ; Antileukotriene-D4 POP:153 ; Cancer-Preventive 525 ; Choleretic 5 ml/man DUKE1992B ; Dermatitigenic M&R495 ; FLavor FEMA 1-30 ARC ; Hypocholesterolemic GAS ; Insectifuge 382 ; Irritant M11 ; Percutaneostimulant CPB38:3086 ; Perfumery ARC

PALMITIC-ACID Seed 55,000 - 65,000 ppm HHB
5-Alpha-Reductase-Inhibitor PMID10830511 ; Antifibrinolytic EMP1:53 ; FLavor FEMA 1 ARC ; Hemolytic BIS ; Hypercholesterolemic GAS ; Lubricant JBH ; Nematicide NIG ; Pesticide DUKE1992B ; Soap JBH

STEARIC-ACID Seed 220,000 - 260,000 ppm HHB
5-Alpha-Reductase-Inhibitor PMID10830511 ; Cosmetic JBH ; FLavor FEMA 2-4,000 ARC ; Hypocholesterolemic GAS ; Lubricant JBH ; Perfumery ARC ; Propecic PMID10830511 ; Suppository JBH

References

382: Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
525: Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
ARC: Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Note: Most ARC numerical data were in mg/dl. I know of no other plant where zinc is more prevalent than other minerals and protein. These data should be viewed as suspect.
BIS: Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp. Note: English translation of Wichtl, 1984,1989).
CPB38:3086: Seki, T., Toeda, C., Kawaguchi, T., Juni, K., Sugibayashi, K., and Morimoto, Y. 1990. Enhanced Transdermal Delivery of Zidovudine in Rats and Human Skin. Chem. Pharm. Bull. 38(11): 3086-3089, 1990.
DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.
EMP1:53: Economic & Medicinal Plant Research, 1: 53.
GAS: Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.)
HHB: List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
JSG: J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
M&R495: Jim Duke's personal files
M11: Merck 11th Edition
NIG: Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
PMID10830511: Jim Duke's personal files
POP:153: Jim Duke's personal files
PR4:33: Jim Duke's personal files

ppm = parts per million
tr = trace

Phytochemical Database, USDA - ARS - NGRL, Beltsville Agricultural Research Center, Beltsville, Maryland
Thu May 16 15:38:10 EDT 2002

Please send questions and comments to:

James A. Duke (E-Mail: JimDuke@cpcug.org)
or
Stephen M. Beckstrom-Sternberg (E-Mail: SteveBS@nhgri.nih.gov)

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WebMaster (E-Mail: WebMaster@ars-grin.gov)

The USDA does not recommend self diagnosis or self medication. Please see the disclaimer for more information.