Acetogenin Comparison


Graviola (Annona muricata) has 82 different acetogenin chemicals (in 10 distinct types).
Mountain Graviola (Annona montana) contains as much annonacin (one of the main chemicals studied)
as regular graviola does. . . and it has 26 more acetogenin chemicals not found in graviola (in 6 distinct types)


Type of Acetogenin

Graviola

Mountain

Graviola

Paw Paw

Type 1: Vicinal dihydroxylated and olefinic linear acetogenins

7

-

-

Type 2: Olefenic and acetylenic linear acetogenins

9

-

-

Type 3: Mono-epoxy olefenic acetogenins

5

-

-

Type 4: Bis-epoxy acetogenins

3

1

-

Type 5: Dihydroxylated acetogenins

8

-

-

Type 6 Trihydroxylated and dihydroxylated ketonic acetogenins

4

2

3

Type 7: Tetrahydroxylated and trihydroxylated ketonic acetogenins

9

10

5

Type 8: Polyhydroxylated and tetrahydroxylated ketonic acetogenins

12

7

-

Type 9: THF a-monohydroxylated acetogenins

21

-

-

Type 10: Mono-THF iso-acetogenins

1

2

4

Type 11: THF-Hydroxy acetogenins

-

4

-

Type 12: Trihydroxylated and tetrahydroxylated acetogenins

-

-

4

Type 13: Trihydroxylated, dihydroxylated ketonic, tetrahydroxylated

and pentahydroxylated acetogenins

-

-

9

Type 14: Adjacent bis-THF a-monohydroxylated acetogenins

3

-

1

Type 15: Non-adjacent bis-THF acetogenins

-

-

-

Type 16: Iso-bis-THF acetogenins

-

-

1

Type 17: Non-adjacent THF–THP acetogenins

-

2

-

Total acetogenins documented in the species

82

28

27



Acetogenins Found in Three Annonaceae Plants


Annona muricata

(Graviola)


graviola cont.

Asimina triloba

(Paw Paw)

1. cohibin-A .

8. muricatocin-B

6. asiminenin-B

1. cohibin-B

8. muricatocin-C

6. cis-murisolin

1. cohibin-C

9. annopentocin-A

6. murisolin-A

1. cohibin-A

9. annopentocin-B

7. asitrilobin-A

1. cohibin-B

9. annopentocin-C

7. asitrilobin-B

1. cohibin-C

9. gigantetrocin-B

7. asitrilobin-C

1. cohibin-D

9. muricatalin

7. asitrilobin-D

1. montecristin

9. muricatetrocin-A

7. asitrocin

1. muricatenol

9. muricatetrocin-B

10. asitrocinone

1. murihexol

9. muricatin-A

10. annonacinone-A

2. muridienin-1

9. muricatin-B

10. gigantetrocinone

2. muridienin-2

9. muricoreacin

10. murisolinone

2. muridienin-3

9. muricin-A

12. asimicin

2. muridienin-4

9. muricin-B

12. OH-asimicin

2. chatenaytrienin-1

9. muricin-C

12. OH-trilobacin

2. chatenaytrienin-2

9. muricin-D

12. trilobacin

2. chatenaytrienin-3

9. muricin-E

13. bullatin

2. chatenaytrienin-4

9. muricin-F

13. bullanin

2. muricadienin

9. muricin-H

13. trilobin

3. epomuricenin-A

9. muricin-I

13. asitribin

3. epomuricenin-B

9. murihexocin-A

13. asiminocin

3. epoxymurin-A

9. murihexocin-B

13. bullatetrocin

3. epoxymurin-B

9. murihexocin-C

13. asiminacin

3. sabadelin

10. annomuricinone-D

13. asimin

4. diepomuricanin-A

14. annocatacin-A

13. asiminecin

4. corepoxylone

14. annocatacin-B

14. asimilobin

4. coronin

14. robustocin

15. trilobalicin

5. solamin

 

16. trilobacinone

5. cis-solamin

Annona montana

(Mountain graviola)

 

5. cis-panatellin

4. diepoxymontin

 

5. cis-uvariamicin-IV

6. montalicin-A

 

5. cis-uvariamicin-I

6.montalicin-B

 

5. cis-reticulatacin

7. annonacin

 

5. 15-palmitoylsolamin

7. annomontacin

 

5. 15-oleylsolamin

7. annomontanin-A

 

6. murisolin

7. cis-annoreticuin

 

6. corossolin

7. montalicin-C

 

6. corossolone

7. montalicin-D

 

6. cis-reticulatacin

7. montalicin-E

 

7. annonacin

7. montalicin-F

 

7. annomutacin

7. montalicin-I

 

7. cis-annonacin

7. montalicin-J

 

7. cis-annonacinone

8. annomonicin

 

7. cis-annomontacin

8. montanacin

 

7. cis-goniothalamicin

8. montacin

 

7. arianacin

8. cis-montacin

 

7. muricin-G

8. annomontanin-B

 

7. javoricin

8. montanacin-B

 

8. annohexocin

8. montanacin-C

 

8. muricatalicin

10. montanacin-G

 

8. annomuricin-E

10. montanacin-F

 

8. muricapentocin

11. annomontanin-C

 

8. muricatatin-C

11. montanacin-H

 

8. annomuricin-A

11. montanacin-I

 

8. annomuricin-B

11. montanacin-J

 

8. annomuricin-C

17. montanacin-D

 

8. muricatin-C

17. montanacin-E

 

8. muricatocin-A

 

 







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