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Amazon
PANCREAS SUPPORT*
120 capsules (650 mg each)
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A synergistic formula of 6 rainforest botanicals traditionally used in South America for maintaining healthy blood sugar levels.* For more information on the individual ingredients in Amazon Pancreas Support, follow the links provided below to the plant database files in the Tropical Plant Database.
Each rainforest botanical in this professional formula has been sustainably harvested in the Amazon Rainforest. Click here to learn more about our rainforest ingredients and wild harvesting methods. This product contains no binders, fillers, or exipients and is 100% finely milled natural plants. This product is backed by Raintree's Unconditional Guarantee.
Ingredients: A proprietary blend of pedra hume caá, pata de vaca, chanca piedra, stevia, bitter melon, and neem. This formula is 100% pure natural ground plants. No binders, fillers or other additives are used. These plants have grown naturally in the richness of the Amazon without any pesticides or fertilizers and they are non-irradiated and non-fumigated.
Suggested Use: Take 2-3 capsules twice daily.
Contraindications:
- Not to be used during pregnancy or while breast-feeding.
- This formula contains plants which have demonstrated hypoglycemic actions in animals and/or humans. Diabetics who wish to this formula need to be monitored carefully as medications may need adjustments.
- Those with hypoglycemia should not take this formula.
Drug Interactions: May enhance the effect of antidiabetic medications and insulin. May enhance the effect of hypotensive, diuretic and hypocholesterolemic medications.
Other Practitioner Observations: Several plants in this formula have been documented to reduce blood pressure in animal studies. Individuals with low blood pressure should be monitored for this possible effect.
A 120 capsule bottle is $29.95 each
Or buy 3 bottles for $28.95 each
Or buy 6 bottles for $26.95 each
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Print a PDF Amazon Pancreas Support Brochure
Please note that this is a professional product offered by health practitioners and it is not available in retail stores. Click here to see a list of practitioners who use our products.
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Third-Party Published Research*
This proprietary Raintree product has not been the subject of any clinical research. A partial listing of third-party published research on each herbal ingredient in the formula is shown below. Please refer to the plant database files by clicking on the plant names below to see all available documentation and research on each plant ingredient.
Pedra Hume caá (Myrcia salicifolia, multiflora)
Zucchi, O. L., et al. “Characterization of hypoglycemiant plants by total reflection X-ray fluorescence
spectrometry.” Biol. Trace Elem. Res. 2005; 103(3): 277-90.
Matsuda, H., et al. “Structural requirements of flavonoids and related compounds for aldose reductase
inhibitory activity.” Chem. Pharm. Bull. (Tokyo). 2002; 50(6): 788–95.
Matsuda, H. “Antidiabetic principles of natural medicines. V. Aldose reductase inhibitors from Myrcia multiflora
DC. (2): Structures of myrciacitrins III, IV, and V.” Chem. Pharm. Bull. 2002; 50(3): 429-31.
Yoshikawa, M., et al. “Antidiabetic principles of natural medicines. II. Aldose reductase and alpha-glucosidase
inhibitors from Brazilian natural medicine, the leaves of Myrcia multiflora DC (myrtaceae): structures of
myrciacitrins I and II and myrciaphenones A and B.” Chem. Pharm. Bull. 1998; 46(1): 113–19.
Pepato, M. T., et al. “Assessment of the antidiabetic activity of Myrcia uniflora extracts in streptozotocin diabetic
rats." Diabetes Res. 1993; 22(2): 49–57.
Russo, E. M., et al. “Clinical trial of Myrcia uniflora and Bauhinia forficata leaf extracts in normal and diabetic
patients." Braz. J. Med. Biol. Res. 1990; 23(1): 11–20.
Schmeda-Hirschmann, G., et al. “Preliminary pharmacological studies on Eugenia uniflora leaves: xanthine
oxidase inhibitory activity." J. Ethnopharmacol. 1987; 21(2): 183–86.
Chaudhry, P. S., et al. “Inhibition of human lens aldose reductase by flavonoids, sulindac and indomethacin.”
Biochem. Pharmacol. 1983; 32(13): 1995–98.
Grune, U., et al. “Sobre o principio antidiabetico da pedra-hume-caá, Myrcia multiflora (Lam)." Thesis 1979;
Federal University of Rio de Janeiro.
Brune, U., et al. “Myrcia spaerocarpa, D.C., planta diabetica.” V Simposio de Plantas Medicinais do Brasil, Sao
Paulo-SP, Brazil, 1978; 74 (September 4–6).
Mendes dos Reis Arruda, L., et al. “Efeito hipoglicemiante induzido pelo extracto das raizes de Myrcia citrifolia
(pedra-hume-caa), esudo famacologico preliminar." V Simposio de Plantas Medicinais do Brasil, Sao Paulo-SP, Brazil, 1978; 74 (September 4–6).
Varma, S. D., et al. “Flavonoids as inhibitors of lens aldose reductase.” Science 1975; 188(4194): 1215–16.
Coutinho, A. B. Tese de Catedra. Faculdade de Medicina de Recife. Recife, Brazil, 1938.
Pata de Vaca (Bauhinia forficata)
Estrada, O., et al. “Evaluation of flavonoids from Bauhinia megalandra leaves as inhibitors of glucose-6-
phosphatase system.” Phytother. Res. 2005; 19(10): 859-63.
Vasconcelos, F., et al. “Insulin-like effects of Bauhinia forficata aqueous extract upon Tityus serrulatus scorpion
envenoming.” J. Ethnopharmacol. 2004 Dec; 95(2-3): 385-92.
Jorge, A. P., et al. “Insulinomimetic effects of kaempferitrin on glycaemia and on 14C-glucose uptake in rat
soleus muscle.” Chem. Biol. Interact. 2004 Oct; 149(2-3): 89-96.
Pinheiro, T. S., et al. “Comparative assessment of kaempferitrin from medicinal extracts of Bauhinia forficata “
J. Pharm. Biomed Anal. 2006 Jan 16;
Fuentes, O., et al. “Hypoglycemic activity of Bauhinia candicans in diabetic induced rabbits.” Fitoterapia. 2004
Sep; 75(6): 527-32.
Pepato, M. T., et al. “Evaluation of toxicity after one-months treatment with Bauhinia forficata decoction in
streptozotocin-induced diabetic rats.” BMC Complement. Altern. Med. 2004 Jun 8; 4: 7.
de Sousa, E., et al. “Hypoglycemic effect and antioxidant potential of kaempferol-3,7-O-(alpha)-dirhamnoside
from Bauhinia forficata leaves.” J. Nat. Prod. 2004; 67(5): 829-32.
Lino, S., et al. “Antidiabetic activity of Bauhinia forficata extracts in alloxan-diabetic rats.” Biol. Pharm. Bull.
2004; 27(1): 125-7.
Pepato, M. T., et al. “Anti-diabetic activity of Bauhinia forficata decoction in streptozotocin-diabetic rats." J.
Ethnopharmacol. 2002 July; 81(2): 191–97.
Silva, F. R., et al. “Acute effect of Bauhinia forficata on serum glucose levels in normal and alloxan-induced
diabetic rats." J. Ethnopharmacol. 2002; 83(1–2): 33–7.
Lemus, I., et al. “Hypoglycemic activity of four plants used in Chilean popular medicine.” Phytother. Res. 1999;
13(2): 91–4.
Miyake, E. T., et al. “Caracterizacao farmacognostica de pata-de-vaca (Bauhinia fortificata)." Rev. Bras.
Farmacogn. 1986; 1(1): 56–68.
Almeida, R., et al. “Levantamento da flora medicinal de uso no tratamento da diabete e alguns resultados
experimentais.” VIII Simposio de Plantas Medicinais do Brasil, Manaus-AM, Brazil. September 4–6, 1984, 23.
Chanca Piedra (Phyllanthus niruri)
Raphael, K. R., et al. “Hypoglycemic effect of methanol extract of Phyllanthus amarus Schum & Thonn on
alloxan induced diabetes mellitus in rats and its relation with antioxidant potential.” Indian J. Exp. Biol. 2002;
40(8): 905-9.
Khanna, A. K., et al. "Lipid lowering activity of Phyllanthus niruri in hyperlipemic rats." J. Ethnopharmacol.
2002; 82(1): 19-22.
Srividya, N., et al. “Diuretic, hypotensive and hypoglycaemic effect of Phyllanthus amarus.” Indian J. Exp. Biol.
1995; 33(11): 861–64.
Shimizu, M., et al. “Studies on aldose reductase inhibitors from natural products. II. Active components of a
Paraguayan crude drug, ‘paraparai mi,’ Phyllanthus niruri.” Chem. Pharm. Bull. (Tokyo) 1989; 37(9): 2531–32.
Umarani, D., et al. “Ethanol induced metabolic alterations and the effect of Phyllanthus niruri in their reversal.”
Ancient Sci. Life 1985; 4(3): 174–80.
Ramakrishnan, P. N., et al. “Oral hypoglycaemic effect of Phyllanthus niruri (Linn.) leaves.” Indian J. Pharm.
Sci. 1982; 44(1): 10–12.
Stevia (Stevia rebaudiana)
Chang, J. C., et al. “Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats.” Horm. Metab.
Res. 2005; 37(10): 610-6.
Chen, T. H., et al. “Mechanism of the hypoglycemic effect of stevioside, a glycoside of Stevia rebaudiana.”
Planta Med. 2005; 71(2): 108-13.
Dyrskog, S. E., et al. “Preventive effects of a soy-based diet supplemented with stevioside on the development
of the metabolic syndrome and type 2 diabetes in Zucker diabetic fatty rats.” Metabolism. 2005; 54(9): 1181-8.
Abudula, R., et al. “Rebaudioside A potently stimulates insulin secretion from isolated mouse islets: studies on
the dose-, glucose-, and calcium-dependency.” Metabolism. 2004; 53(10): 1378-81.
Lailerd, N., et al. “Effects of stevioside on glucose transport activity in insulin-sensitive and insulin-resistant rat
skeletal muscle.” Metabolism. 2004; 53(1): 101-7.
Gregersen, S., et al. “Antihyperglycemic effects of stevioside in type 2 diabetic subjects.” Metabolism. 2004;
53(1):73-6.
Raskovic, A., et al. “Joint effect of commercial preparations of Stevia rebaudiana Bertoni and sodium
monoketocholate on glycemia in mice.” Eur. J. Drug Metab. Pharmacokinet. 2004 Apr-Jun; 29(2): 83-6.
Raskovic, A., et al. “Glucose concentration in the blood of intact and alloxan-treated mice after pretreatment with commercial preparations of Stevia rebaudiana (Bertoni).” Eur. J. Drug Metab. Pharmacokinet. 2004 Apr-Jun;29(2):87
Gardana, C., et al. “Metabolism of stevioside and rebaudioside A from Stevia rebaudiana extracts by human
microflora.” J. Agric. Food Chem. 2003 Oct; 51(22): 6618-22.
Koyama, E., et al. “Absorption and metabolism of glycosidic sweeteners of stevia mixture and their aglycone,
steviol, in rats and humans.” Food Chem.Toxicol. 2003; 41(6): 875-83.
Jeppesen, P. B., et al. “Stevioside acts directly on pancreatic beta cells to secrete insulin: actions independent
of cyclic adenosine monophosphate and adenosine triphosphate-sensitive K+-channel activity.” Metabolism.
2000; 49(2): 208–14.
Yamamoto, N. S., et al. “Effect of steviol and its structural analogues on glucose production and oxygen uptake
in rat renal tubules.” Experientia. 1985; 41(1): 55–7.
Curi, R., et al. “Effect of Stevia rebaudiana on glucose tolerance in normal adult humans." Braz. J. Med. Biol.
Res. 1986; 19(6): 771–74.
Suzuki, H., et al. “Influence of the oral administration of stevioside on the levels of blood glucose and liver
glycogen in intact rats.” Nogyo Kagaku Zasshi 1977; 51(3): 45.
Oviedo, C. A., et al. “Hypoglycemic action of Stevia rebaudiana.” Excerpta Medica. 1970; 209: 92.
Bitter Melon (Momordica charantia)
Omar, S., et al. "Hypoglycemic effect of the seeds of Momordica charantia." Fitoterapia. 2007; 78(1): 46-7.
Ojewole, J., et al. "Hypoglycaemic and hypotensive effects of Momordica charantia Linn (Cucurbitaceae) whole-plant aqueous extract in rats." Cardiovasc. J. S. Afr. 2006 Sep-Oct; 17(5): 227-32.
Mahomoodally, M., et al. "Effect of exogenous ATP on Momordica charantia Linn. (Cucurbitaceae) induced inhibition of d-glucose, l-tyrosine and fluid transport across rat everted intestinal sacs in vitro." J. Ethnopharmacol. 2006 Sep 26;
Lans, C. "Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus." J. Ethnobiol. Ethnomedicine. 2006 Oct 13; 2:45.
Chuang, C., et al. "Fractionation and identification of 9c, 11t, 13t-conjugated linolenic acid as an activator of PPARalpha in bitter gourd (Momordica charantia L.)." J. Biomed. Sci. 2006 Nov; 13(6): 763-72.
Krawinkel, M., et al. "Bitter gourd (Momordica charantia): A dietary approach to hyperglycemia." Nutr. Rev. 2006; 64(7 Pt 1): 331-7.
Harinantenaina, L., et al. "Momordica charantia constituents and antidiabetic screening of the isolated major compounds." Chem. Pharm. Bull. 2006; 54(7): 1017-21.
Abd El Sattar, E., et al. "Some toxicological studies of Momordica charantia L. on albino rats in normal and alloxan diabetic rats." J. Ethnopharmacol. 2006 Nov; 108(2): 236-42.
Yibchok-Anun. S., et al. "Slow acting protein extract from fruit pulp of Momordica charantia with insulin secretagogue and insulinomimetic activities." Biol. Pharm. Bull. 2006 Jun;29(6):1126-31.
Jung, M., et al. "Antidiabetic agents from medicinal plants." Curr. Med. Chem. 2006; 13(10): 1203-18.
Kumar, G., et al. "Effect of bitter gourd and spent turmeric on constituents of glycosaminoglycans in different tissues in streptozotocin induced diabetic rats." Mol. Cell. Biochem. 2006 Jun; 286(1-2) :53-8.
Reyes, B., et al. "Anti-diabetic potentials of Momordica charantia and Andrographis paniculata and their effects on estrous cyclicity of alloxan-induced diabetic rats." J. Ethnopharmacol. 2006 Apr; 105(1-2): 196-200.
Khan, B., et al. "Hypogylcemic activity of aqueous extract of some indigenous plants." Pak. J. Pharm. Sci. 2005; 18(1): 62-4.
Zheng, Z.X., et al. “The hypoglycemic effects of crude polysaccharides extract from Momordica charantia in mice.” Wei Sheng Yan Jiu. 2005 May; 34(3): 361-3.
Reyes, B. A., et al. “Anti-diabetic potentials of Momordica charantia and Andrographis paniculata and their effects on estrous cyclicity of alloxan-induced diabetic rats.” J. Ethnopharmacol. 2005 Nov 16;
Sathishsekar, D., et al. “Beneficial effects of Momordica charantia seeds in the treatment of STZ-induced diabetes in experimental rats.” Biol. Pharm. Bull. 2005; 28(6): 978-83.
Shetty, A. K., et al. “Effect of bitter gourd (Momordica charantia) on glycaemic status in streptozotocin induced diabetic rats.” Plant Foods Hum. Nutr. 2005 Sep; 60(3): 109-12.
Kumar Shetty, A., et al. “Bitter gourd (Momordica charantia) modulates activities of intestinal and renal disaccharidases in streptozotocin-induced diabetic rats.” Mol. Nutr. Food Res. 2005; 49(8): 791-6.
Chaturvedi, P., et al. “Effect of Momordica charantia on lipid profile and oral glucose tolerance in diabetic rats.” Phytother. Res. 2004; 18(11): 954-6.
Vikrant, V., et al. “Treatment with extracts of Momordica charantia and Eugenia jambolana prevents hyperglycemia and hyperinsulinemia in fructose fed rats.” J. Ethnopharmacol. 2001; 76(2): 139–43.
Miura, T., et al. “Hypoglycemic activity of the fruit of the Momordica charantia in type 2 diabetic mice.” J. Nutr. Sci. Vitaminol. 2001; 47(5): 340–44.
Raza, H., et al. “Modulation of xenobiotic metabolism and oxidative stress in chronic streptozotocin-induced diabetic rats fed with Momordica charantia fruit extract.” J. Biochem. Mol. Toxicol. 2000; 14(3): 131–39.
Ahmad, N., et al. “Effect of Momordica charantia (Karolla) extracts on fasting and postprandial serum glucose levels in NIDDM patients.” Bangladesh Med. Res. Counc. Bull. 1999; 25(1): 11–13.
Ahmed, I., et al. “Effects of Momordica charantia fruit juice on islet morphology in the pancreas of the streptozotocin-diabetic rat.” Diabetes Res. Clin. Pract. 1998; 40(3): 145–51.
Sarkar, S., et al. “Demonstration of the hypoglycemic action of Momordica charantia in a validated animal model of diabetes.” Pharmacol. Res. 1996; 33(1): 1–4.
Ali, L., et al. “Studies on hypoglycemic effects of fruit pulp, seed and whole plant of Momordica charantia on normal and diabetic model rats.” Planta Med. 1993; 59(5): 408–12.
Akhtar, M. S. “Trial of Momordica charantia Linn (Karela) powder in patients with maturity-onset diabetes.” J. Pak. Med. Assoc. 1982; 32(4): 106–7.
Neem (Azadirachta indica)
Sritanaudomchai, H., et al. “Quinone reductase inducers in Azadirachta indica A. Juss flowers, and their
mechanisms of action.” Asian Pac. J. Cancer Prev. 2005 Jul-Sep; 6(3): 263-9.
Gholap, S, et al. “Hypoglycaemic effects of some plant extracts are possibly mediated through inhibition in
corticosteroid concentration.” Pharmazie. 2004; 59(11): 876-8.
Gupta, S., et al. “Protective role of extracts of neem seeds in diabetes caused by streptozotocin in rats.” J.
Ethnopharmacol. 2004 Feb; 90(2-3): 185-9.
Halim, E. M. “Lowering of blood sugar by water extract of Azadirachta indica and Abroma augusta in diabetes
rats.”
Indian J. Exp. Biol. 2003; 41(6): 636-40.
Halder, N., et al. “Lens aldose reductase inhibiting potential of some indigenous plants.” J. Ethnopharmacol.
2003 May; 86(1): 113-6.
Khosla, P, et al. “A study of hypoglycaemic effects of Azadirachta indica (Neem) in normal and alloxan diabetic
rabbits.” Indian J. Physiol. Pharmacol. 2000; 44(1): 69-74.
Chattopadhyay, R. R. “A comparative evaluation of some blood sugar lowering agents of plant origin.” J.
Ethnopharmacol. 1999; 67(3): 367-72.
Chattopadhyay, R. R. “Possible mechanism of antihyperglycemic effect of Azadirachta indica leaf extract: part
V.” J. Ethnopharmacol. 1999; 67(3): 373-6.
Chattopadhyay, R. R. “Possible mechanism of antihyperglycemic effect of Azadirachta indica leaf extract. Part
IV.” Gen. Pharmacol. 1996; 27(3): 431-4.
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* The statements contained herein have not been evaluated
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