Many biologically active compounds have been discovered in anamu, including flavonoids, triterpenes, steroids and sulfur compounds.* For more complete information on this unique rainforest plant, please see plant database file on anamu. To see pictures of anamu, click here.
Raintree's anamu has been sustainably wild-harvested in the Brazilian Amazon. Click here to learn more about our rainforest ingredients and wild harvesting methods. This product contains no binders, fillers, or exipients and is 100% finely milled natural anamu. This product is backed by Raintree's Unconditional Guarantee.
Traditional Uses:* for cancer and leukemia; for immune disorders (to stimulate immune function and immune cell production); for colds, flu, and viruses; for Candida and other yeast infections; for urinary tract infections
Ingredients: 100% pure anamu whole herb (Petiveria alliacea). This product is non-irradiated and non-fumigated. It is a wild harvested product—grown naturally in the Brazilian Amazon without any pesticides or fertilizers.
Suggested Use: Take 2-3 capsules twice daily or as directed by a health care professional.
Contraindications: Methanol extracts of anamu were reported to cause uterine contractions in animal studies, therefore, it is contraindicated in pregnancy.
Drug Interactions: None published. Due to anamu’s natural coumarin content, however, it is conceivable that it might potentiate the effects of coumadin (Warfarin®).
Other Observations:
Anamu contains a low concentration of coumarin, which has a blood thinning effect. People with blood disorders, such as hemophilia, should be monitored closely for this possible effect.
This plant has been shown to have hypoglycemic effects in mice. People with hypoglycemia should be monitored more closely for this possible effect.
A 100 capsule bottle is $18.95 each
Or buy 3 bottles for $17.95 each
Or buy 6 bottles for $15.95 each
Third Party Published Research*
This Raintree product has not been the subject of any clinical research.
All available third-party research on anamu can be found at PubMed/Medline.
A partial listing of the published research on anamu is shown below:
Cytotoxic & Anticancerous Actions: An, H., et al. "Synthesis and anti-tumor evaluation of new trisulfide derivatives." Bioorg. Med. Chem. Lett. 2006 Sep; 16(18): 4826-9.
Williams, L. A., et al. "In vitro anti-proliferation/cytotoxic activity of sixty natural products on the human SH-SY5Y neuroblastoma cells with specific reference to dibenzyl trisulphide." West Indian Med. J. 2004 Sep; 53(4): 208-19.
Ruffa, M. J., et al. “Cytotoxic effect of Argentine medicinal plant extracts on human hepatocellular carcinoma cell line.” J.
Ethnopharmacol. 2002; 79(3): 335-39.
Mata-Greenwood, E., et al. “Discovery of novel inducers of cellular differentiation using HL-60 promyelocytic cells.”
Anticancer Res. 2001; 21(3B): 1763-70.
Rosner, H., et al. “Disassembly of microtubules and inhibition of neurite outgrowth, neuroblastoma cell proliferation, and MAP kinase tyrosine dephosphorylation by dibenzyl trisulphide.” Biochem. Biophys. Acta 2001;1540(2): 166-77.
Jovicevic, L., et al. “In vitro antiproliferative activity of Petiveria alliacea L. on several tumor cell lines.” Pharmacol. Res.
1993; 27(1): 105-06.
Rossi, V., et al. “Antiproliferative effects of Petiveria alliacea on several tumor cell lines.” Pharmacol. Res. Suppl. 1990;
22(2): 434.
Yan, R., et al. “Astilbin selectively facilitates the apoptosis of interleukin-2-dependent phytohemaglutinin-activated Jurkat
cells.” Pharmacol. Res. 2001; 44(2): 135-39.
Weber, U. S., et al. “Antitumor activities of coumarin, 7-hydroxy-coumarin and its glucuronide in several human tumor cell
lines”. Res. Commun. Mol. Pathol. Pharmacol. 1998; 99(2): 193-206.
Bassi, A. M., et al. “Comparative evaluation of cytotoxicity and metabolism of four aldehydes in two hepatoma cell lines.”
Drug Chem. Toxicol. 1997 Aug; 20(3): 173-87.
Immunostimulant Actions: Queiroz, M. L., et al. “Cytokine profile and natural killer cell activity in Listeria monocytogenes infected mice treated orally
with Petiveriaalliacea extract. Immunopharmacol. Immunotoxicol. 2000 Aug; 22(3): 501-18.
Quadros, M. R., et al. “Petiveria alliacea L. extract protects mice against Listeria monocytogenes infection—effects on
bone marrow progenitor cells.” Immunopharmacol. Immunotoxicol. 1999 Feb; 21(1): 109-24.
Williams, L., et al. “Immunomodulatory activities of Petiveria alliaceae L.” Phytother. Res. 1997; 11(3): 251253.
Rossi, V., “Effects of Petiveria alliacea L. on cell immunity.” Pharmacol. Res. 1993; 27(1): 111-12.
Marini, S., “Effects of Petiveria alliacea L. on cytokine production and natural killer cell activity.” Pharmacol. Res. 1993;
27(1): 107-08.
Anti-inflammatory & Pain-Relieving Actions: Gomes, P. B., et al. “Study of antinociceptive effect of isolated fractions from Petiveria alliacea L. (tipi) in mice.” Biol.
Pharm. Bull. 2005; 28(1): 42-6.
Lopes-Martins, R. A., et al. “The anti-inflammatory and analgesic effects of a crude extract of Petiveria alliacea L.
(Phytolaccaceae).” Phytomedicine. 2002; 9(3): 245-48.
Dunstan, C. A., et al. “Evaluation of some Samoan and Peruvian medicinal plants by prostaglandin biosynthesis and rat
ear oedema assays.” J. Ethnopharmacol. 1997 Jun; 57(1): 35-56.
Germano, D., et al. “Pharmacological assay of Petiveria alliaceae. Oral anti-inflammatory activity and gastrotoxicity of a
hydro alcoholic root extract.” Fitoterapia. 1993; 64(5): 459-467.
Germano, D. H., et al. “Topical anti-inflammatory activity and toxicity of Petiveria alliaceae.” Fitoterapia. 1993; 64(5): 459-67.
de Lima, T. C., et al. “Evaluation of antinociceptive effect of Petiveria alliacea (Guine) in animals.” Mem. Inst. Oswaldo
Cruz. 1991; 86 Suppl 2: 153-58.
Di Stasi, L. C., et al. “Screening in mice of some medicinal plants used for analgesic purposes in the state of Saõ Paulo.”
J. Ethnopharmacol. 1988; 24(2/3): 205–11.
Antimicrobial & Antiparasitic Actions: Kim, S., et al. “Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.” J. Ethnopharmacol. 2006 Mar; 104(1-2): 188-92.
Kubec, R., et al. “The lachrymatory principle of Petiveria alliacea.” Phytochemistry. 2003 May; 63(1): 37-40.
Ruffa, M. J., et al. “Antiviral activity of Petiveria alliacea against the bovine diarrhea virus. Chemotherapy 2002; 48(3): 144-47.
Benevides, P. J., et al. “Antifungal polysulphides from Petiveria alliacea L.” Phytochemistry. 2001; 57(5): 743-7.
Caceres, A., et al. “Plants used in Guatemala for the treatment of protozoal infections. I. Screening of activity to bacteria,
fungi and American trypanosomes of 13 native plants.” J. Ethnopharmacol. 1998 Oct; 62(3): 195-202.
Berger, I., et al. “Plants used in Guatemala for the treatment of protozoal infections: II. Activity of extracts and fractions of
five Guatemalan plants against Trypanosoma cruzi.” J. Ethnopharmacol. 1998 Sep; 62(2): 107-15.
Hoyos, L., et al. “Evaluation of the genotoxic effects of a folk medicine, Petiveria alliaceae (Anamu).” Mutat. Res. 1992;
280(1): 29-34.
Caceres, A., et al. “Plants used in Guatemala for the treatment of dermatophytic infections. I. Screening for antimycotic
activity of 44 plant extracts.” J. Ethnopharmacol. 1991; 31(3): 263-76.
Misas, C.A.J., et al. “The biological assessment of Cuban plants. III.” Rev. Cub. Med. Trop. 1979; 31(1): 21–27.
Von Szczepanski, C., et al. “Isolation, structure elucidation and synthesis of an antimicrobial substance from Petiveria
alliacea.” Arzneim-Forsch 1972; 22: 1975–.
Feng, P., et al. “Further pharmacological screening of some West Indian medicinal plants.” J. Pharm. Pharmacol. 1964;
16: 115.
Hypoglycemic Actions: Lans, C. A. "Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus." J. Ethnobiol. Ethnomedicine. 2006 Oct 13; 2: 45.
Lores, R. I., et al. “Petiveria alliaceae L. (anamu). Study of the hypoglycemic effect.” Med. Interne. 1990; 28(4): 347–52.
RELATED PRODUCTS:
Anamu can be found as an ingredient in these proprietary Raintree formulas:
Anamu Tech Report -- A Technical Plant Data Report is available for anamu.
* The statements contained herein have not been evaluated by the Food and Drug Administration.
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